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R. Lewis Dark: Complete Human DNA Profiling as a STAT Test
MOST OF YOU ARE UNFAMILIAR WITH A NEW SCIENTIFIC PRIZE that is in the
planning stage. On January 27, The Wall Street Journal published a story
that disclosed the plans of the X Prize Foundation to award a prize,
totaling between $5 million and $20 million, to the team that first
decodes the full DNA of 100 or more people in just a few weeks.
If the X Prize Foundation seems familiar to you, it is the same group that
awarded the $10 million prize to the team that developed SpaceShipOne,
which in October 2004 became the first manned space vehicle to launch
from earth, reach space and return safely twice in one week.
What is intriguing about this planned new award for DNA sequencing
is that J. Craig Venter, Ph.D., is collaborating with the X Prize
Foundation. It was Venter who launched the private project to map the
human genome in 1998 and developed ways to accelerate gene sequencing.
(See TDR, June 15, 1998.)
The goal of this new prize is to encourage development of faster,
cheaper gene-sequencing technologies. According to The Wall Street
Journal, today's technology can allow a team to sequence the entire
human genome in about six months, at a cost of $20 million. Experts
believe this cost may be driven down to $100,000 within a few years.
My fellow readers, can you imagine what this technology might eventually
allow us to do? For a reasonable cost, a full human genome could
be sequenced in minutes and that clinical information delivered to the
patient's physician. In our life times, we may see complete human DNA
profiling done as a STAT test. Boy, wouldn't that change laboratory medicine
the way we know it today? It could happen. After all, in the lifetime
of some of our oldest doctors, they have seen the discovery of DNA lead
to useful genetic tests and therapies.
Of course, the skeptics among you have good arguments why it may take decades for anything like this to happen. I understand that viewpoint. However, as the industrial age yielded to the information age in recent
decades, it seems like the genetic age may supplant the information age at an
ever-accelerating pace. Maybe Star Trek's vision wasn't so far-fetched...
Nurse Chapel, would you please bring the Tricorder to Bones?
Many Trends in AP Spell
Lots of Change Ahead
Our biannual list expands to 11 trends,
larger number points to swifter evolution
CEO SUMMARY: Every second year, THE DARK REPORT releases its list of key trends in anatomic pathology. These trends help
shape an understanding about the state of the pathology profession.
Our current list includes 11 identifiable trends. This is
not an auspicious sign for pathologists who prefer things to
remain the same. Eleven distinct trends are themselves evidence
that plenty of important changes are happening.
Sonora Quest Receives
Highest AZ Quality Award
Only healthcare provider ever to receive
Arizona's Governor's Award for quality
CEO SUMMARY: After several years of intense effort to implement quality management systems and Six Sigma
techniques throughout its organization, Sonora Quest
Laboratories earned the Arizona Quality Program's highest
honor—the Governor's Award for Quality. This is an accomplishment
without precedent in the laboratory industry, either in the United States or internationally.
INTELLIGENCE:
EARLY-STAGE TEST
FOR LUNG CANCER
SHOWS PROMISE
OML ON THE MOVE
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